WEEK 45 (2023) – Gut Health Revisited: Exploring the Gut Microbiome’s Role in Type 2 Diabetes

This week, I stepped in to write the newsletter and decided to revisit a topic that has gained significant attention in recent years – gut health. I’ll delve into the fascinating world of the gut microbiome and its intricate relationship with a prevalent health concern: Type 2 Diabetes.

The Gut Microbiome: A Thriving Ecosystem Within

Your gut is not just a simple digestive organ; it’s a complex ecosystem inhabited by trillions of microorganisms, collectively known as the gut microbiome. This microbial community comprises bacteria, viruses, fungi, and other organisms, all working together to maintain your health. The gut microbiome has a profound influence on digestion, nutrient absorption, immune system function, and even mental health.

Type 2 Diabetes: A Growing Concern

Type 2 Diabetes is a metabolic disorder characterised by insulin resistance and high blood sugar levels. It affects millions of people worldwide, and its prevalence is steadily increasing. While genetics and lifestyle factors like diet and physical activity play a role in the development of the condition, researchers are discovering that the gut microbiome might also be a key player in this health puzzle.

Research Highlights

A growing body of research supports the notion that an imbalanced gut microbiome, known as dysbiosis, may contribute to the development of Type 2 Diabetes. Here are a few key findings from recent studies:

Microbial Diversity: Studies suggest that individuals with greater microbial diversity in their gut tend to have a lower risk of developing Type 2 Diabetes. A diverse microbiome is associated with better metabolic health.

Inflammation: An imbalanced gut microbiome can lead to chronic low-grade inflammation, a risk factor for insulin resistance and Type 2 Diabetes.

Short-Chain Fatty Acids (SCFAs): Certain gut bacteria produce SCFAs, like butyrate, which can help regulate blood sugar levels and improve insulin sensitivity.

Dietary Impact: Your diet is crucial in shaping your gut microbiome. A diet rich in fibre and plant-based foods can promote a healthier microbial community, potentially reducing the risk of Type 2 Diabetes.

Research and Probiotic Supplementation

While evidence suggests a connection between the gut microbiome and the risk of type 2 diabetes, there is no clear causal link and that modulating the gut microbiome can be an effective treatment for obesity and the risk of type 2 diabetes.

However, the aim of a recent study in Greece set about to evaluate the effect of probiotic supplementation on markers of type 2 diabetes like glycemic control (HbA1C).

This randomised, double-blind, placebo-controlled trial was conducted over six months on individuals with type 2 diabetes at the Diabetes Center of Laiko General Hospital in Athens. Either a multi-strain probiotic or a placebo was given to the 91 patients.

Blood chemistries were taken every three months, and associated markers were analysed. After six months, the probiotic group showed a significant reduction in HbA1C, fasting blood glucose and total cholesterol.

The researchers concluded that probiotic supplementation is a promising intervention for those with type 2 diabetes and may reduce the risk of further complications associated with the disease. However, they acknowledge that the sample size was relatively small and many variables can affect individuals, so more research is needed.

Taking Action for Better Gut Health

While research is ongoing, there are steps you can take to support a healthy gut microbiome:

Eat a Balanced Diet: Prioritise fibre-rich foods, whole grains, legumes, fruits, and vegetables to nourish your gut microbiome.

Probiotics and Prebiotics: Consider incorporating probiotic-rich foods like yoghurt and kimchi into your diet, and include prebiotic foods like garlic, onions, and leeks to feed beneficial gut bacteria.

Manage Stress: Chronic stress can disrupt the gut-brain axis. Implement stress-reduction techniques like meditation and mindfulness.

Consult a Healthcare Professional: If you have concerns about your gut health or diabetes risk, consult a healthcare provider who can give personalised guidance.

In conclusion, the connection between the gut microbiome and Type 2 Diabetes is an exciting area of research, and it underscores the importance of maintaining a healthy gut. But this is just the tip of the iceberg. Ongoing research delves into the connection between our microbiome and immunity, mental health, skin health, and so much more. Remember, the choices you make in terms of diet and lifestyle can have a profound impact on your gut health and overall well-being.

Best wishes for a healthy and vibrant future!


Supplement Recommendations


14 viable strains of friendly bacteria, with 9 billion colony-forming units per serving (2 capsules). It also includes fructooligosaccharides to help support the growth of healthy bacteria in the digestive tract.

Sodium Butyrate
Butyric acid is a short-chain fatty acid produced naturally in the colon by the bacterial fermentation of dietary fibres and is known as a postbiotic. Supplementation is commonly used to aid healing in the digestive tract and support microbial diversity.



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