Welcome to this week’s newsletter, where we are focusing on teeth and gums. World Oral Health Day is observed annually on 20 March to raise awareness of oral health issues and the importance of oral hygiene. While we often associate dental care with the maintenance of healthy teeth and gums, research shows a close relationship between oral health and systemic diseases, particularly heart disease. Therefore, in this week’s newsletter, we delve into compelling evidence linking gum disease to cardiovascular health and the potential role of Coenzyme Q10 in promoting gum health.

The Connection Between Gum Disease and Systemic Health

Gum disease, or periodontal disease, is a chronic inflammatory condition affecting the tissues surrounding the teeth. It begins with the accumulation of plaque, a sticky film of bacteria, on the teeth. If left untreated, it progresses to gingivitis, characterised by inflamed and bleeding gums, and can advance to periodontitis, leading to tooth loss and systemic complications.

Researchers have long suspected a connection between gum disease and systemic health conditions, particularly cardiovascular diseases like heart disease and stroke. Several studies have explored the mechanisms underlying this association. Chronic inflammation, a hallmark of gum disease, is believed to contribute to systemic inflammation, which plays a pivotal role in the development and progression of cardiovascular diseases. Moreover, the bacteria involved in gum disease can enter the bloodstream, potentially triggering inflammation in the arteries and increasing the risk of atherosclerosis, a condition characterised by plaque buildup.

Research Insights

A growing body of evidence supports the link between gum disease and heart disease. A systematic review and meta-analysis published in the Journal of Periodontology analysed data from over 80 studies. They found a significant association between periodontitis and an increased risk of cardiovascular diseases. Another study published in the American Heart Association journal Circulation demonstrated that individuals with severe gum disease had a 20% higher risk of developing heart disease compared to those with healthy gums.

Furthermore, research suggests that treating gum disease may have a beneficial effect on cardiovascular health. A study published in the New England Journal of Medicine found that intensive treatment of periodontitis reduced markers of systemic inflammation and improved endothelial function, a key determinant of cardiovascular health.

Coenzyme Q10: A Nutrient for Gum Health

Evidence suggests that coenzyme Q10 (CoQ10) may hold promise for supporting and maintaining gum health. CoQ10, a naturally occurring antioxidant found in every cell of the body, plays a crucial role in energy production and antioxidant defence. Research indicates that CoQ10 supplementation may benefit individuals with gum disease by reducing inflammation and supporting tissue repair.

A randomised controlled trial published in the Journal of Clinical Periodontology investigated the effects of CoQ10 supplementation on gum health in individuals with periodontitis. The study found that participants who received CoQ10 supplements exhibited significant improvements in gum inflammation and attachment loss compared to the placebo group.

Moreover, CoQ10’s antioxidant properties may help combat oxidative stress, a contributing factor to gum disease progression. By neutralising free radicals and protecting against tissue damage, CoQ10 supplementation could complement conventional periodontal therapy and promote better oral health outcomes.

When considering CoQ10 supplementation for promoting gum health, it’s helpful to opt for the ubiquinol form. Ubiquinol is the reduced, active form of CoQ10, which is more readily absorbed by the body than ubiquinone, the oxidised form. Studies have shown that ubiquinol supplementation leads to higher plasma levels of CoQ10 and may offer superior antioxidant benefits. Since oxidative stress is implicated in gum disease progression, choosing ubiquinol ensures maximum efficacy in combating inflammation and supporting tissue repair, thereby optimising oral health outcomes.


As we observe World Oral Health Day, it is important to recognise the intricate connection between oral health and systemic well-being. The evidence linking gum disease to cardiovascular diseases demonstrates the importance of comprehensive dental care in mitigating systemic health risks. Additionally, Coenzyme Q10 is a valuable nutrient for promoting gum health, offering potential benefits in reducing inflammation and supporting tissue repair. We can work towards better overall health and well-being by embracing a holistic approach to oral care and integrating strategies to maintain optimal gum health.

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