The Hidden Reason Why Curcumin Protects Your Kidney Health

Curcumin has been found to have protective benefits for kidney health, according to recent animal studies. While the exact mechanisms behind these effects are unknown, the findings hold promise for anyone looking for potential natural treatment against the development of renal fibrosis.

Fibrosis is a common indicator of chronic kidney disease, due to the formation of internal scar tissue that can have devastating effects and ultimately lead to end-stage kidney failure. 

Chinese researchers investigated the anti-fibrotic effects on epithelial-to-mesenchymal transition (EMT) that’s induced by transforming growth factor-B1 (TGF-B1) along with the mechanism by which it influences the phosphatidylinositol-3 kinase (PI3K)/Akt pathway. These findings were published in the journal, Biological and Pharmaceutical Bulletin. [1]

Researchers treated human kidney tubular epithelial cells (HKCs) with either TGF-B1 or Curcumin alone, and also with a combination of both. They used 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) to assess the effect of Curcumin on cell growth.

What researchers found is that taking a low dose promoted kidney cells and after 72 hours, Curcumin caused the cells to maintain their epithelial form and structure, even when the dose was maintained. 

Researchers noted that Curcumin also decreased proteins that may induce tumor or cancerous cell growth (EMT), while helping them to reduce stress and prevent activation of Akt/mTOR pathway activity. This pathway plays a role in regulating cell cycles and longevity. 

Based on these findings, researchers therefore concluded that Curcumin is an alternative treatment for kidney fibrosis because of how it promotes human kidney cells while inhibiting any Akt/mTOR pathway activity.

This latest Curcumin study provides a further strong body of evidence suggesting that Curcumin’s powerful anti-inflammatory and antioxidant properties can support your kidney health, amongst other powerful health benefits. 

 

References:

[1] https://www.jstage.jst.go.jp/article/bpb/40/1/40_b16-00364/_article

Recommended Reading

Helping Kidney Health, By The Book – This book can guide you towards finding relief for kidney problems and support for improved kidney health. Contains a detailed plan designed to boost the health of your kidneys, when it’s combined with a naturally healthy lifestyle the advice in this book will result in improved symptoms towards your long term good health. Available from Good Health Naturally and Naturally Healthy News.

Recommended Examples

CurcuminX4000™ with Fenugreek Seed Extract Provides all the benefits of Curcumin with Meriva®, the most clinically studied Curcumin on the market. Provides 600mg Meriva (root) Curcuma longa extract per serving. Now with 150mg of Fenugreek Seed Extract for enhanced bioavailability and absorption. Suitable for vegetarians and vegans. 180 capsules. Available from Good Health Naturally.

Serranol™ – This is a combination formula of 160,000IU Serrapeptase, Ecklonia Cava, CurcuminX4000™ and Vitamin D3. These core nutrients, combined together, can provide a super supplement that studies show targets dozens of health and age-related issues. Available from Good Health Naturally.

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