Inflammation – the body’s natural repair response – is increasingly being seen as the real culprit in heart disease. And now it’s being linked to cancer after researchers found that even the most aggressive breast cancer tumours were responding to anti-inflammatory drugs.
Anti-inflammatories, and especially JAK inhibitors, designed to treat rheumatoid arthritis, disturb the anti-viral pathways of triple-negative tumours, the most aggressive form of breast cancer.
These pathways drive inflammation, which seems to cause the tumours to grow and spread, say researchers at the Washington University School of Medicine.
(Source: Cell reports, 2014; 7(2): 514)